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Article

Longitudinal Analyses of Mutational Subclonal Architecture and Tumor Subtypes in Recurrent Bladder Cancer.

International journal of molecular sciences - 8 May 2023

Ryu Daeun, Kim Tae-Min, Lee Yun-Hee, Ha U-Syn

Abstract excerpt

Longitudinal tumor sequencing of recurrent bladder cancer (BC) can facilitate the investigation of BC progression-associated genomic and transcriptomic alterations. In this study, we analyzed 18 tumor specimens including distant and locoregional metastases obtained during tumor progression for five BC patients using whole-exome and transcriptome sequencing. Along with the substantial level of intratumoral...

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Identifiers

PMID: 37176124
DOI: 10.3390/ijms24098418
PMCID: PMC10179737

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