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Article

Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus

16 Jan 2017

Abstract excerpt

BACKGROUND: In 2014, Western Africa experienced an unanticipated explosion of Ebola virus infections. What distinguishes fatal from non-fatal outcomes remains largely unknown, yet is key to optimising personalised treatment strategies. We used transcriptome data for peripheral blood taken from infected and convalescent recovering patients to identify early stage host factors that are associated with acute illness...

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PMID: 28100256
DOI: 10.1186/s13059-016-1137-3

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