Article
Mutations and expressions of breast cancer 1/2 in lung cancer.
Thoracic cancer - 1 Jun 2023
Yan Bokang, Xie Bin, Huang Meiyuan, Guo Jiaxing, Sun Jingyue, Chen Jielin, Tao Yongguang, Xiao Desheng
Abstract excerpt
BACKGROUND: Breast cancer 1 (BRCA1) and breast cancer 2 (BRCA2) tumor suppressor genes play crucial roles in DNA repair and regulation of transcription. Mutations in these genes are closely associated with the occurrence of cancers. However, the mutation status of BRCA gene in central south Chinese lung cancer patients remains unclear, and its expression levels in lung cancer also need to be further explored....
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