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Article

Low frequency of AIP mutations in patients with young-onset sporadic pituitary macroadenomas.

Journal of endocrinological investigation - 1 Nov 2023

Gaspar L M, Gonçalves C I, Saraiva C, Cortez L, Amaral C, Nobre E, Lemos M C

Abstract excerpt

PURPOSE: Mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene cause familial isolated pituitary adenomas (FIPA). AIP mutations have also been found in patients with apparently sporadic pituitary adenomas, particularly in young patients with large adenomas. The aim of this study was to determine the frequency of AIP germline mutations in patients with young-onset sporadic pituitary...

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Identifiers

PMID: 37149543
DOI: 10.1007/s40618-023-02083-7
PMCID: PMC10558361

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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