Article
Screening for AIP gene mutations in a Han Chinese pituitary adenoma cohort followed by LOH analysis.
European journal of endocrinology - 1 Dec 2013
Cai Feng, Zhang Yi-Dan, Zhao Xiuli, Yang Ya-Kun, Ma Si-Hai, Dai Cong-Xin, Liu Xiao-Hai, Yao Yong, Feng Ming, Wei Jun-Ji, Xing Bing, Jiao Yong-Hui, Wei Zhen-Qing, Yin Zhen-Ming, Zhang Bo, Gu Feng, Wang Ren-Zhi
Abstract excerpt
OBJECTIVE: The aryl hydrocarbon receptor interacting protein gene (AIP) is associated with pituitary adenoma (PA). AIP has not been sequenced in East Asian PA populations, so we performed this study in a Han Chinese cohort. DESIGN: Our study included six familial PA pedigrees comprising 16 patients and 27 unaffected relatives, as well as 216 sporadic PA (SPA) patients and 100 unrelated healthy controls. METHODS:...
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