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Article

Genetic Molecular Subtypes in Optimizing Personalized Therapy for Metastatic Colorectal Cancer.

Current drug targets - 1 Jan 2018

Włodarczyk Marcin, Włodarczyk Jakub, Siwiński Paweł, Sobolewska-Włodarczyk Aleksandra, Fichna Jakub

Abstract excerpt

Colorectal cancer (CRC) is a heterogeneous disease entity in terms of both molecular carcinogenesis and morphologic carcinogenesis multistep pathways. Considerable heterogeneity exists within CRC due to the varied genetic and epigenetic mechanisms involved in different carcinogenesis pathways. A better understanding of pathophysiology of tumors is necessary to develop modern and successful means of treatment in...

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Identifiers

PMID: 30073926
DOI: 10.2174/1389450119666180803122744

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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