Article
Phylogenomic discovery of deleterious mutations facilitates hybrid potato breeding.
Cell - 25 May 2023
Wu Yaoyao, Li Dawei, Hu Yong, Li Hongbo, Ramstein Guillaume P, Zhou Shaoqun, Zhang Xinyan, Bao Zhigui, Zhang Yu, Song Baoxing, Zhou Yao, Zhou Yongfeng, Gagnon Edeline, Särkinen Tiina, Knapp Sandra, Zhang Chunzhi, Städler Thomas, Buckler Edward S, Huang Sanwen
Abstract excerpt
Hybrid potato breeding will transform the crop from a clonally propagated tetraploid to a seed-reproducing diploid. Historical accumulation of deleterious mutations in potato genomes has hindered the development of elite inbred lines and hybrids. Utilizing a whole-genome phylogeny of 92 Solanaceae and its sister clade species, we employ an evolutionary strategy to identify deleterious mutations. The deep...
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