Analysis of progenitor genomes offers insights to reduce deleterious burden in hybrid potato breeding.

doi:10.1093/plcell/koag227

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Analysis of progenitor genomes offers insights to reduce deleterious burden in hybrid potato breeding.

The Plant cell - 4 Aug 2026

Liu Weizhi, Hu Yong, Ding Zihui, Yu Qing, Peng Haixu, Zhang Xianyi, Zhao Xinyao, Zhou Yao, Zhai Jingjing, Zhou Yongfeng, Ramstein Guillaume P, Huang Sanwen, Wu Yaoyao

Abstract excerpt

Hybrid potato breeding aims to transition potato from clonal tetraploid to seed-propagated diploid. However, this process is hindered by historically accumulated deleterious variants, resulting in weak field performance of existing homozygous inbreds and compromised heterosis in hybrids. To accelerate genome design for hybrid potato breeding, it is essential to understand how deleterious variation was reshaped...

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PMID: 42531465
DOI: 10.1093/plcell/koag227

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