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Redefining normal breast cell populations using long noncoding RNAs

5 May 2023

Abstract excerpt

Single-cell RNAseq has allowed unprecedented insight into gene expression across different cell populations in normal tissue and disease states. However, almost all studies rely on annotated gene sets to capture gene expression levels and sequencing reads that do not align to known genes are discarded. Here, we discover thousands of long noncoding RNAs (lncRNAs) expressed in human mammary epithelial cells and...

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PMID: 37144467
DOI: 10.1093/nar/gkad339

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