Article

Unraveling lncRNA Diversity at a Single Cell Resolution and in a Spatial Context across Different Cancer Types

2024-08-12

Abstract excerpt

Long non-coding RNAs (lncRNAs) play pivotal roles in gene regulation and disease, including cancer. Overcoming the limitations of lncRNA analysis with bulk data, we analyzed single-cell and spatial transcriptomics data to uncover 354937 novel lncRNAs and their functions across 13 cancer types. LncRNA functions were assessed by identifying their cell-type specificity and distinct spatial distributions across differ...

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Literature Corpus work: 980dfb7e-902c-56b7-abfd-d9cc6ea320bf
DOI: 10.1101/2024.08.12.607523

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