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Article

A single-cell atlas of the healthy breast tissues reveals clinically relevant clusters of breast epithelial cells

1 Mar 2021

Abstract excerpt

Single-cell RNA sequencing (scRNA-seq) is an evolving technology used to elucidate the cellular architecture of adult organs. Previous scRNA-seq on breast tissue utilized reduction mammoplasty samples, which are often histologically abnormal. We report a rapid tissue collection/processing protocol to perform scRNA-seq of breast biopsies of healthy women and identify 23 breast epithelial cell clusters. Putative...

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PMID: 33763657
DOI: 10.1016/j.xcrm.2021.100219

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