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Tetraspanins in human epithelial malignancies

15 Sept 2010

Abstract excerpt

Transmembrane proteins of the tetraspanin superfamily are implicated in a broad spectrum of cellular processes in many biological systems in both health and disease. Tetraspanins form specialized membrane microdomains on the cell surface which control cell proliferation and migration through various adhesion and growth factor receptors. Recent extensive research has shown that expression of various tetraspanins...

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PMID: 20938929
DOI: 10.1002/path.2779

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