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Article

Investigating effect modification between childhood maltreatment and genetic risk for cardiovascular disease in the UK Biobank.

PloS one - 1 Jan 2023

Urquijo Helena, Soares Ana Gonçalves, Fraser Abigail, Howe Laura D, Carter Alice R

Abstract excerpt

Cardiovascular disease (CVD) is influenced by genetic and environmental factors. Childhood maltreatment is associated with CVD and may modify genetic susceptibility to cardiovascular risk factors. We used genetic and phenotypic data from 100,833 White British UK Biobank participants (57% female; mean age = 55.9 years). We regressed nine cardiovascular risk factors/diseases (alcohol consumption, body mass index...

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Identifiers

PMID: 37141292
DOI: 10.1371/journal.pone.0285258
PMCID: PMC10159177

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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