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Article

LoLoPicker: detecting low allelic-fraction variants from low-quality cancer samples.

Oncotarget - 6 Jun 2017

Carrot-Zhang Jian, Majewski Jacek

Abstract excerpt

INTRODUCTION: Although several programs are designed to identify variants with low allelic-fraction, further improvement is needed, especially to push the detection limit of low allelic-faction variants in low-quality, "noisy" tumor samples. RESULTS: We developed LoLoPicker, an efficient tool dedicated to calling somatic variants from next-generation sequencing (NGS) data of tumor sample against the matched...

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Identifiers

PMID: 28416765
DOI: 10.18632/oncotarget.16144
PMCID: PMC5514890

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