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Article

The effect of traditional diet on glucose homoeostasis in carriers and non-carriers of a common TBC1D4 variant in Greenlandic Inuit: a randomised crossover study.

The British journal of nutrition - 14 Dec 2023

Lewis Jack Ivor, Lind Mads Vendelbo, Møller Grith, Hansen Torben, Pedersen Hanne, Christensen Marie Mathilde Bjerg, Laursen Jens Christian, Nielsen Sara, Ottendahl Charlotte B, Larsen Christina V Lytken, Stark Ken D, Bjerregaard Peter, Jørgensen Marit E, Lauritzen Lotte

Abstract excerpt

Consumption of traditional foods is decreasing amid a lifestyle transition in Greenland as incidence of type 2 diabetes (T2D) increases. In homozygous carriers of a TBC1D4 variant, conferring postprandial insulin resistance, the risk of T2D is markedly higher. We investigated the effects of traditional marine diets on glucose homoeostasis and cardio-metabolic health in Greenlandic Inuit carriers and non-carriers...

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Identifiers

PMID: 37129117
DOI: 10.1017/S000711452300106X
PMCID: PMC10632723

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