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Article

Modulation of cytoskeleton in cardiomyopathy caused by mutations in LMNA gene.

American journal of physiology. Cell physiology - 1 Jun 2023

Chatzifrangkeskou Maria, Le Dour Caroline, Muchir Antoine

Abstract excerpt

Dilated cardiomyopathy caused by mutations in LMNA, encoding A-type lamins (i.e., LMNA cardiomyopathy), is characterized by a left ventricle enlargement and ultimately results in poor cardiac contractility associated with conduction defects. Despite current strategies to aggressively manage the symptoms, the disorder remains a common cause of sudden death and heart failure with decreased ejection fraction....

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Identifiers

PMID: 37125775
DOI: 10.1152/ajpcell.00471.2022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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