Article
Genetic proxies for calcium channel blockers and cancer: a Mendelian randomization study.
Journal of human hypertension - 1 Nov 2023
Fan Bohan, Schooling C Mary, Zhao Jie V
Abstract excerpt
Calcium channel blockers (CCBs) are commonly prescribed antihypertensives. However, concerns exist about potential off-target effects on cancer. This Mendelian randomization (MR) study examined the associations of genetic proxies for CCBs with the risk of cancer. We used published genetic proxies in the target genes of CCBs as instruments, and obtained MR estimates by applying them to large studies of 17...
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