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Circulating immune cell phenotypes are associated with age, sex, CMV, and smoking status in the Framingham Heart Study offspring participants.

Aging - 27 Apr 2023

Fang Yuan, Doyle Margaret F, Chen Jiachen, Mez Jesse, Satizabal Claudia L, Alosco Michael L, Qiu Wei Qiao, Lunetta Kathryn L, Murabito Joanne M

Abstract excerpt

Understanding the composition of circulating immune cells with aging and the underlying biologic mechanisms driving aging may provide molecular targets to slow the aging process and reduce age-related disease. Utilizing cryopreserved cells from 996 Framingham Heart Study (FHS) Offspring Cohort participants aged 40 and older (mean 62 years, 48% female), we report on 116 immune cell phenotypes including monocytes,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37116193
DOI: 10.18632/aging.204686
PMCID: PMC10258017

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