Article
Modeling SARS-CoV-2 nucleotide mutations as a stochastic process.
PloS one - 1 Jan 2023
Lim Kai Rong Maverick, Kuruoglu Ercan Engin, Chan Wai Kin Victor
Abstract excerpt
This study analyzes the SARS-CoV-2 genome sequence mutations by modeling its nucleotide mutations as a stochastic process in both the time-series and spatial domain of the gene sequence. In the time-series model, a Markov Chain embedded Poisson random process characterizes the mutation rate matrix, while the spatial gene sequence model delineates the distribution of mutation inter-occurrence distances. Our...
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