Article
Inferring the Association between the Risk of COVID-19 Case Fatality and N501Y Substitution in SARS-CoV-2.
Viruses - 8 Apr 2021
Zhao Shi, Lou Jingzhi, Chong Marc K C, Cao Lirong, Zheng Hong, Chen Zigui, Chan Renee W Y, Zee Benny C Y, Chan Paul K S, Wang Maggie H
Abstract excerpt
As COVID-19 is posing a serious threat to global health, the emerging mutation in SARS-CoV-2 genomes, for example, N501Y substitution, is one of the major challenges against control of the pandemic. Characterizing the relationship between mutation activities and the risk of severe clinical outcomes is of public health importance for informing the healthcare decision-making process. Using a likelihood-based...
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