Comparison of circulating tumor DNA between African American and Caucasian patients with metastatic castrate-resistant prostate cancer post-abiraterone and/or enzalutamide.

doi:10.1002/pros.24544

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Comparison of circulating tumor DNA between African American and Caucasian patients with metastatic castrate-resistant prostate cancer post-abiraterone and/or enzalutamide.

The Prostate - 1 Aug 2023

Jang Albert, Lanka Sree M, Huang Minqi, Casado Crystal V, Caputo Sydney A, Sweeney Patrick L, Gupta Kanika, Pocha Olivia, Habibian Nicholas, Hawkins Madeline E, Lieberman Alexandra D, Schwartz Jennifer, Jaeger Ellen B, Miller Patrick J, Layton Jodi L, Barata Pedro C, Lewis Brian E, Ledet Elisa M, Sartor Oliver

Abstract excerpt

BACKGROUND: African American men are much more likely than Caucasian men to be diagnosed with and to die of prostate cancer. Genetic differences likely play a role. The cBioPortal database reveals that African American men with prostate cancer have higher rates of CDK12 somatic mutations compared to Caucasian men. However, this does not account for prior prostate cancer treatments, which are particularly...

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PMID: 37113064
DOI: 10.1002/pros.24544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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