Article
Surveillance of cfDNA Hot Spot Mutations in NSCLC Patients during Disease Progression.
International journal of molecular sciences - 9 Apr 2023
Sestokaite Agne, Gedvilaite Vaida, Cicenas Saulius, Sabaliauskaite Rasa, Jarmalaite Sonata
Abstract excerpt
Non-small cell cancer (NSCLC) has been identified with a great variation of mutations that can be surveyed during disease progression. The aim of the study was to identify and monitor lung cancer-specific mutations incidence in cell-free DNA as well as overall plasma cell-free DNA load by means of targeted next-generation sequencing. Sequencing libraries were prepared from cell-free DNA (cfDNA) isolated from 72...
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