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Article

Impact of PNPLA3 and TM6SF2 polymorphisms on the prognosis of patients with MASLD and type 2 diabetes mellitus.

Liver international : official journal of the International Association for the Study of the Liver - 1 Apr 2024

Lavrado Natália Coelho, Salles Gil Fernando, Cardoso Claudia Regina Lopes, de França Paulo Henrique Condeixa, Melo Maria Fernanda Di Guimarães Gonçalves, Leite Nathalie Carvalho, Villela-Nogueira Cristiane Alves

Abstract excerpt

BACKGROUND/AIMS: Longitudinal studies assessing the impact of genetic polymorphisms on outcomes in patients with Type 2 Diabetes Mellitus (T2DM) and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) are scarce. This study aimed to evaluate the effect of PNPLA3 and TM6SF2 risk alleles on hepatic and extrahepatic outcomes in T2DM-MASLD individuals. METHODS: Patients' polymorphisms were analysed as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 38293718
DOI: 10.1111/liv.15845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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