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ClC Chloride Channels in Gram-Negative Bacteria and Its Role in the Acid Resistance Systems

14 Apr 2023

Abstract excerpt

Pathogenic bacteria that colonize the human intestinal tract have evolved strategies to overcome acidic conditions when they pass through the gastrointestinal tract. Amino acid-mediated acid resistance systems are effective survival strategies in a stomach that is full of amino acid substrate. The amino acid antiporter, amino acid decarboxylase, and ClC chloride antiporter are all engaged in these systems, and...

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PMID: 37100762
DOI: 10.4014/jmb.2303.03009

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