DNA Repair Enzyme XRCC4 30 bp Indel Intron 3 Locus Significant Association with Predisposition of Cataract in Senility.

doi:10.1007/s12010-023-04533-7

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DNA Repair Enzyme XRCC4 30 bp Indel Intron 3 Locus Significant Association with Predisposition of Cataract in Senility.

Applied biochemistry and biotechnology - 1 Jan 2024

Kafeel Sanober, Bizenjo Neelam, Shivji Shams Salman, Keran Asifa, Hashim Zehra, Nawab Syeda Nuzhat

Abstract excerpt

Impaired DNA damage repair cascade can disrupt the lens transparency due to aging-associated oxidative stress. The aim of study was to assess the association of 30 bp indel mutation (rs28360071) in XRCC4 gene with susceptibility of cataract in senility. The study followed case-control design with a total of n = 200 participants and divided equally into senile cataract patients and control groups. Conventional...

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PMID: 37099126
DOI: 10.1007/s12010-023-04533-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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