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Article

Study of association between pre-senile cataracts and rs11615 of ERCC1, rs13181 of ERCC2, and rs25487 of XRCC1 polymorphisms in a Spanish population.

Ophthalmic genetics - 1 Jan 2000

López-Valverde Gloria, Garcia-Martin Elena, Fernández-Mateos Javier, Cruz-González Fernando, Larrosa-Povés José M, Polo-Llorens Vicente, Pablo-Júlvez Luis E, González-Sarmiento Rogelio

Abstract excerpt

BACKGROUND: The purpose of this study was to attempt to determine if the presence of certain polymorphisms in the DNA repair genes (ERCC1, ERCC2, and XRCC1) is associated with pre-senile cataract development. MATERIALS AND METHODS: We performed a retrospective study over three groups of patients. The first group with pre-senile cataract was formed by 72 patients younger than 55 years with cataract surgery. The...

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Source

Identifiers

PMID: 27668351
DOI: 10.1080/13816810.2016.1217548

Genes

ERCC1
ERCC2
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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