Article
Genetic polymorphisms in DNA repair genes OGG1, APE1, XRCC1, and XPD and the risk of age-related cataract.
Ophthalmology - 1 May 2012
Zhang Yi, Zhang Lan, Song Zhen, Sun Dong Lin, Liu Han Ruo, Fu Song Bin, Liu Dong Rui, Liu Ping
Abstract excerpt
PURPOSE: To analyze the association of the polymorphisms in 8-oxoguanine glycosylase-1 (OGG1), X-ray repair cross-complementing-1 (XRCC1), and AP endonuclease-1 (APE1) genes in the base excision repair pathway and xeroderma pigmentosum complementation group D (XPD) in the nucleotide excision repair pathway with the risk of cataract in a Chinese population. DESIGN: Case-control study. PARTICIPANTS: Subjects with...
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