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Article

Downregulated ESRP1/2 promotes lung metastasis of bladder carcinoma through altering FGFR2 splicing and macrophage polarization

5 Apr 2023

Abstract excerpt

Introduction Lung metastasis occurs in parts of the bladder carcinoma (BC) patients but represents the highest severity and a poor outcome of the disease. The molecular mechanism underlying lung metastasis of BC is not fully understood. Fibroblast growth factor receptor 2 (FGFR2) signaling plays a substantial role in the BC cell growth and invasion. In this study, we assessed the regulation of the alternative...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 37090731
DOI: 10.3389/fimmu.2023.1161273

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