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Article

Mutant CDKN2A regulates P16/p14 expression by alternative splicing in renal cell carcinoma metastasis.

Pathology, research and practice - 1 Jul 2021

Sun Qingrong, Chen Siyi, Hou Yingjian, Wen Xiaodong, Teng Xiaodong, Zhang Honghe, Lai Chong, Lai Maode

Abstract excerpt

OBJECTIVE: Metastatic renal cell carcinoma (mRCC) is the important factor for patient mortality, meanwhile gene mutation constantly changes cancer prognosis in tumor process. Exploring the driver mutation in mRCC process become more and more important. MATERIALS AND METHODS: We obtained the 15 paired primary and metastatic mRCC samples and analyzed specific mutation genes in the metastatic foci (SMGs) by next...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 34022680
DOI: 10.1016/j.prp.2021.153453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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