Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of hemopexin plasma levels in patients with age-related macular degeneration.

Molecular vision - 1 Jan 2022

Lauwen Susette, Bakker Bjorn, de Jong Eiko K, Fauser Sascha, Hoyng Carel B, Lefeber Dirk J, den Hollander Anneke I

Abstract excerpt

Purpose: A protein quantitative trait locus (pQTL) analysis recently revealed a strong association between hemopexin (HPX) levels and genetic variants at the complement factor H (CFH) locus. In this study, we aimed to determine HPX plasma levels in patients with age-related macular degeneration (AMD) and to compare them with those in controls. We also investigated whether genetic variants at the CFH locus are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement Factor H
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Macular Degeneration

Share to Polymorphism, Single Nucleotide

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 37089696
PMCID: PMC10115365

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of hemopexin plasma levels in patients with age-related macular degeneration.PMID 37089696Read ↗

Common haplotypes at the CFH locus and low-frequency variants in CFHR2 and CFHR5 associate with systemic FHR concentrations and age-related macular degeneration.Semantic proximity Read ↗

Beyond factor H: The impact of genetic-risk variants for age-related macular degeneration on circulating factor-H-like 1 and factor-H-related protein concentrations.Semantic proximity Read ↗

Systemic complement levels in patients with age-related macular degeneration carrying rare or low-frequency variants in the CFH gene.Semantic proximity Read ↗

A prospective assessment of the Y402H variant in complement factor H, genetic variants in C-reactive protein, and risk of age-related macular degeneration.Semantic proximity Read ↗

Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration.Semantic proximity Read ↗

Plasma biomarkers of oxidative stress and genetic variants in age-related macular degeneration.Semantic proximity Read ↗

Measurement of factor H variants in plasma using variant-specific monoclonal antibodies: application to assessing risk of age-related macular degeneration.Semantic proximity Read ↗

Evaluation of serum and ocular levels of membrane attack complex and C-reactive protein in CFH-genotyped human donors.Semantic proximity Read ↗

Complement factor H and hemicentin-1 in age-related macular degeneration and renal phenotypes.Semantic proximity Read ↗

Complement factor H Y402H and C-reactive protein polymorphism and photodynamic therapy response in age-related macular degeneration.Semantic proximity Read ↗

Complement factor H variant p.Y402H in pseudoxanthoma elasticum patients.Semantic proximity Read ↗

Screening of DNA-variants in the properdin gene (CFP) in age-related macular degeneration (AMD).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.