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Article

Screening of DNA-variants in the properdin gene (CFP) in age-related macular degeneration (AMD).

Molecular immunology - 1 Mar 2010

Seitsonen Sanna, Onkamo Päivi, Torniainen Suvi, Ihalainen Milla, Immonen Ilkka, Meri Seppo, Järvelä Irma

Abstract excerpt

Several variants in the complement cascade genes (complement factor H [CFH], C2, C3, CFB, and Serping1) have been reported to associate with age-related macular degeneration (AMD). Of these, a member of the complement alternative pathway, CFH, represents the highest risk. As properdin (P) is also...

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Source

Identifiers

PMID: 20122735
DOI: 10.1016/j.molimm.2010.01.001

Genes

CFP
CFH
CFB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20122735-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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