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Article

Whole genome DNA methylation and mutational profiles identify novel changes in proliferative verrucous leukoplakia.

Oral surgery, oral medicine, oral pathology and oral radiology - 1 Jun 2023

Okoturo Eyituoyo, Green Daniel, Clarke Kim, Liloglou Triantafyllos, Boyd Mark T, Shaw Richard J, Risk Janet M

Abstract excerpt

OBJECTIVE: Proliferative verrucous leukoplakia (PVL) is a rare form of oral leukoplakia with a relatively high transformation rate resulting in oral squamous cell carcinoma (OSCC). Molecular analysis of PVL at the genome level is limited and has only identified molecular similarities between PVL and OSCC. However, the clinical profile of PVL suggests that molecular differences may be more important. STUDY DESIGN:...

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Share to Carcinoma, Squamous Cell
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Head and Neck Neoplasms

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Share to Squamous Cell Carcinoma of Head and Neck

Source

Identifiers

PMID: 37088660
DOI: 10.1016/j.oooo.2023.03.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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