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Article

Frequent alterations of p16INK4a and p14ARF in oral proliferative verrucous leukoplakia.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2008

Kresty Laura A, Mallery Susan R, Knobloch Thomas J, Li Junan, Lloyd Mary, Casto Bruce C, Weghorst Christopher M

Abstract excerpt

Proliferative verrucous leukoplakia (PVL) represents a rare but highly aggressive form of oral leukoplakia with > 70% progressing to malignancy. Yet, PVL remains biologically and genetically poorly understood. This study evaluated the cell cycle regulatory genes, p16INK4a and p14ARF, for homozygo...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclin-Dependent Kinase Inhibitor p16

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Source

Identifiers

PMID: 18990760
DOI: 10.1158/1055-9965.EPI-08-0574

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18990760-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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