High incidence of <scp>DNA</scp> ploidy abnormalities and increased <scp>M</scp>cm2 expression may predict malignant change in oral proliferative verrucous leukoplakia

Abstract excerpt

AIMS: To assess the DNA content of cases of oral proliferative verrucous leukoplakia (PVL) and correlate the DNA ploidy findings with the expression of Mcm2, geminin, and Ki67, and with clinicopathological data. METHODS AND RESULTS: DNA quantification was performed by image cytometry using the ACIS III Automated Cellular Imaging System. Expression of Ki67, Mcm2 and geminin was determined by immunohistochemistry....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Head and Neck Cancer Studies
• Share to Nonmelanoma Skin Cancer Studies
• Share to Oral Health Pathology and Treatment