Article
Identifying causal associations between early sexual intercourse or number of sexual partners and major depressive disorders: A bidirectional two-sample Mendelian randomization analysis.
Journal of affective disorders - 15 Jul 2023
Lu Zhe, Sun Yaoyao, Liao Yundan, Kang Zhewei, Feng Xiaoyang, Zhao Guorui, Sun Junyuan, Zhang Yuyanan, Yue Weihua
Abstract excerpt
BACKGROUND: Early sexual intercourse and a greater number of sexual partners have been proved associated with depression. However, the causality of these associations is not clear. METHODS: To unveil the causal associations between sexual factors and major depression disorder (MDD). The bidirectional, two-sample Mendelian randomization (MR) study was conducted, which used genetic variants associated with two...
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