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Article

Investigating the causal relationship between major depressive disorder and benign prostatic hyperplasia: a bidirectional Mendelian randomisation study.

Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society - 1 Nov 2024

Zheng Guanghao, Xiao Shuaiyun, Cheng Yu, Huang Jianbiao, Luo Chengwei, Peng Lifen, Zeng Tao

Abstract excerpt

BACKGROUND: Evidence from various cohort studies indicate a potential association between depressive disorder and benign prostatic hyperplasia (BPH), yet findings are inconsistent. This study employs bidirectional two-sample Mendelian randomisation (MR) analysis to explore the causal relationship between BPH and major depressive disorder (MDD). METHODS: Genetic variants strongly associated with MDD were extracted...

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PMID: 39187931
DOI: 10.1111/psyg.13180

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PGC

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