Article
[Association between polygenic risk score and age at onset of gastric cancer].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 10 Jun 2021
Liu Y Q, Wang T P, Yan C W, Zhu M, Yang M, Wang M Y, Hu Z B, Shen H B, Jin G F
Abstract excerpt
Objective: To explore the association between polygenic risk score (PRS) and age at onset and early-onset risk of gastric cancer (GC). Methods: Gastric cancer cases from existing genome-wide association study were included, and 112 single nucleotide polymorphisms associated with GC risk were used to derive individual PRS. Analysis of variance and Pearson correlation test was used to depict the relationship...
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