Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

House dust mite and Th2 cytokine-mediated epithelial barrier dysfunction attenuation by KL001 in 16-HBE cells

20 Apr 2023

Abstract excerpt

House dust mite (HDM) is a common aeroallergen that can disrupt the airway epithelial barrier leading to dysregulated immune response, resulting in allergic lung diseases such as asthma. Cryptochrome (CRY), a circadian clock gene, plays an important role in the regulation of metabolism, and immune response. It remains unclear whether stabilizing CRY using KL001 can attenuate HDM/Th2 cytokine-induced epithelial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allergic Rhinitis and Sensitization
Share to Asthma and respiratory diseases
Share to Circadian rhythm and melatonin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37079442
DOI: 10.1080/21688370.2023.2203841

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

House dust mite and Th2 cytokine-mediated epithelial barrier dysfunction attenuation by KL001 in 16-HBE cellsPMID 37079442Read ↗

Cryptochrome Loss Drives COPD-like Lung Pathology through Disrupted Alveolar Epithelial Proliferation and Immune HomeostasisSemantic proximity Read ↗

Oxidized phosphatidylcholines induce multiple functional defects in airway epithelial cellsSemantic proximity Read ↗

Epigenetic regulation of epithelial dectin-1 through an IL-33-STAT3 axis in allergic diseaseSemantic proximity Read ↗

Circadian disruption reduces MUC4 expression via clock molecule BMAL1 during dry eye developmentSemantic proximity Read ↗

Epigenetic regulation of epithelial dectin‐1 through an IL‐33‐STAT3 axis in allergic diseaseSemantic proximity Read ↗

Circadian disruption reduces MUC4 expression via the clock molecule BMAL1 during dry eye developmentSemantic proximity Read ↗

MyD88 in lung resident cells governs airway inflammatory and pulmonary function responses to organic dust treatment.Semantic proximity Read ↗

Circadian clock dysfunction of epithelial cells in pulmonary diseasesSemantic proximity Read ↗

Circadian molecular clock disruption in chronic pulmonary diseasesSemantic proximity Read ↗

Bojungikgi-tang improves skin barrier function and immune response in atopic dermatitis mice fed a low aryl hydrocarbon receptor ligand dietSemantic proximity Read ↗

OGG1 inhibitor TH5487 alleviates allergic airway inflammation in miceSemantic proximity Read ↗

Dysregulation of CLOCK gene expression in hyperoxia-induced lung injurySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.