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Article

Developing an Appropriate Evolutionary Baseline Model for the Study of Human Cytomegalovirus.

Genome biology and evolution - 6 Apr 2023

Howell Abigail A, Terbot John W, Soni Vivak, Johri Parul, Jensen Jeffrey D, Pfeifer Susanne P

Abstract excerpt

Human cytomegalovirus (HCMV) represents a major threat to human health, contributing to both birth defects in neonates as well as organ transplant failure and opportunistic infections in immunocompromised individuals. HCMV exhibits considerable interhost and intrahost diversity, which likely influences the pathogenicity of the virus. Therefore, understanding the relative contributions of various evolutionary...

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Identifiers

PMID: 37071785
DOI: 10.1093/gbe/evad059
PMCID: PMC10139446

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