Article
Characterizing human cytomegalovirus reinfection in congenitally infected infants: an evolutionary perspective.
Molecular ecology - 1 Apr 2017
Pokalyuk Cornelia, Renzette Nicholas, Irwin Kristen K, Pfeifer Susanne P, Gibson Laura, Britt William J, Yamamoto Aparecida Y, Mussi-Pinhata Marisa M, Kowalik Timothy F, Jensen Jeffrey D
Abstract excerpt
Given the strong selective pressures often faced by populations when colonizing a novel habitat, the level of variation present on which selection may act is an important indicator of adaptive potential. While often discussed in an ecological context, this notion is also highly relevant in our clinical understanding of viral infection, in which the novel habitat is a new host. Thus, quantifying the factors...
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