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Article

Analysis of gene expression profiles and protein-protein interaction networks in multiple tissues of systemic sclerosis

1 Dec 2019

Abstract excerpt

BACKGROUND: Systemic sclerosis (SSc), a multi-organ disorder, is characterized by vascular abnormalities, dysregulation of the immune system, and fibrosis. The mechanisms underlying tissue pathology in SSc have not been entirely understood. This study intended to investigate the common and tissue-specific pathways involved in different tissues of SSc patients. METHODS: An integrative gene expression analysis of...

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PMID: 31881890
DOI: 10.1186/s12920-019-0632-2

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