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Article

Exploring the causal link between serum amino acids and Parkinson's disease: a Mendelian randomization approach.

Scientific reports - 4 Dec 2024

Cheng Lei, Yan Juntao, Shi Wenting, Zhang Jing, Dong Qingjun, Hu Yiren, Zhou Zhongyan, Ye Qing

Abstract excerpt

This study aimed to explore the causal relationships between multiple blood amino acids (BAAs) and the Parkinson's disease (PD). We downloaded genome-wide association study (GWAS) data for BAAs and PD from the OpenGWAS database, screened single nucleotide polymorphisms (SNPs) from the data, and evaluated the causal relationship between BAA levels and PD using the inverse variance weighted (IVW) method. The...

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Identifiers

PMID: 39632961
DOI: 10.1038/s41598-024-81787-z
PMCID: PMC11618358

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