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Article

HLA-DRB1*15 and Eosinophilia Are Common Among Patients With Systemic Juvenile Idiopathic Arthritis.

Arthritis care & research - 1 Oct 2023

Lerman Alison M, Mahmud Shawn A, Alfath Zineb, Langworthy Benjamin W, Hobday Patricia M, Riskalla Mona M, Binstadt Bryce A

Abstract excerpt

OBJECTIVE: Concern exists that medications used to treat patients with systemic juvenile idiopathic arthritis (JIA), particularly interleukin (IL)-1 and IL-6 blocking agents, might be causing adverse drug reactions and lung disease (systemic JIA-LD). Carriage of HLA-DRB1*15 has been reported as a risk factor for adverse drug reactions among patients with systemic JIA. We performed a retrospective chart review to...

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Identifiers

PMID: 37052526
DOI: 10.1002/acr.25132
PMCID: PMC10524250

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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