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Article

Exome sequencing identifies a novel gene, WNK1, for susceptibility to pelvic organ prolapse (POP).

PloS one - 1 Jan 2015

Rao Shuquan, Lang Jinghe, Zhu Lan, Chen Juan

Abstract excerpt

Pelvic organ prolapse (POP) is a common gynecological disorder; however, the genetic components remain largely unidentified. Exome sequencing has been widely used to identify pathogenic gene mutations of several diseases because of its high chromosomal coverage and accuracy. In this study, we performed whole exome sequencing (WES), for the first time, on 8 peripheral blood DNA samples from representative POP...

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Share to Amino Acid Sequence
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intracellular Signaling Peptides and Proteins

Share to Minor Histocompatibility Antigens

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Share to WNK Lysine-Deficient Protein Kinase 1

Source

Open in PubMed Open full text

Identifiers

PMID: 25739019
DOI: 10.1371/journal.pone.0119482
PMCID: PMC4349638

Genes

WNK1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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