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Single-cell analysis of uterosacral ligament revealed cellular heterogeneity in women with pelvic organ prolapse

7 Feb 2024

Abstract excerpt

Pelvic organ prolapse (POP) markedly affects the quality of life of women, including significant financial burden. Using single-cell RNA sequencing, we constructed a transcriptional profile of 30,452 single cells of the uterosacral ligament in POP and control samples, which has never been constructed before. We identified 10 major cell types, including smooth muscle cells, endothelial cells, fibroblasts,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38326542
DOI: 10.1038/s42003-024-05808-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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