Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhanced inhibition of MHC-I expression by SARS-CoV-2 Omicron subvariants

10 Apr 2023

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) possess mutations that confer resistance to neutralizing antibodies within the Spike protein and are associated with breakthrough infection and reinfection. By contrast, less is known about the escape from CD8+ T cell-mediated immunity by VOC. Here, we demonstrated that all SARS-CoV-2 VOCs possess the ability to suppress major...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19 Clinical Research Studies
Share to SARS-CoV-2 and COVID-19 Research
Share to vaccines and immunoinformatics approaches

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37036977
DOI: 10.1073/pnas.2221652120

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 12 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhanced inhibition of MHC-I expression by SARS-CoV-2 Omicron subvariantsPMID 37036977Read ↗

SARS-CoV-2 Omicron subvariants evolved to promote further escape from MHC-I recognitionSemantic proximity Read ↗

Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariantsSemantic proximity Read ↗

Genetic and Immunological Profiling of Recent SARS-CoV-2 Omicron Variants: Insights into Immune Evasion and Infectivity in Monoinfections and CoinfectionsSemantic proximity Read ↗

T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individualsSemantic proximity Read ↗

Evolutionary characteristics of SARS-CoV-2 Omicron subvariants adapted to the hostSemantic proximity Read ↗

Potential immune evasion of the severe acute respiratory syndrome coronavirus 2 Omicron variantsSemantic proximity Read ↗

SARS-CoV-2 spike T cell responses induced upon vaccination or infection remain robust against OmicronSemantic proximity Read ↗

Evasive Spike Variants Elucidate the Preservation of T Cell Immune Response to the SARS-CoV-2 Omicron Variant.Semantic proximity Read ↗

Ablation of CD8+ T cell recognition of an immunodominant epitope in SARS-CoV-2 Omicron variants BA.1, BA.2 and BA.3Semantic proximity Read ↗

An engineered ACE2 decoy neutralizes the SARS-CoV-2 Omicron variant and confers protection against infection in vivoSemantic proximity Read ↗

SARS-CoV-2 T Cell Responses Elicited by COVID-19 Vaccines or Infection Are Expected to Remain Robust against Omicron.Semantic proximity Read ↗

From Alpha to omicron: The response of T cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.