Article
Phage resistance of Salmonella enterica obtained by transposon Tn5-mediated SefR gene silent mutation.
Journal of basic microbiology - 1 May 2023
Wang Yinfeng, Xuan Guanhua, Lin Hong, Fei Zhenhong, Wang Jingxue
Abstract excerpt
Salmonella enterica contamination is a primary cause of global food poisoning. Using phages as bactericidal alternatives to antibiotics could confront the issue of drug resistance. However, the problem of phage resistance, especially mutant strains with multiple phage resistance, is a critical barrier to the practical application of phages. In this study, a library of EZ-Tn5 transposable mutants of susceptible...
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