Article
CRISPR-Cas12a Biosensor Array for Ultrasensitive Detection of Unamplified DNA with Single-Nucleotide Polymorphic Discrimination.
ACS sensors - 28 Apr 2023
Weng Zhengyan, You Zheng, Li Huijie, Wu Guangfu, Song Yang, Sun He, Fradlin Ava, Neal-Harris Camille, Lin Mengshi, Gao Xue, Zhang Yi
Abstract excerpt
Quantitative polymerase chain reaction as a powerful tool for DNA detection has been pivotal to a vast range of applications, including disease screening, food safety assessment, environmental monitoring, and many others. However, the essential target amplification step in combination with fluore...
Topics
- Humans
- CRISPR-Cas Systems
- Polymorphism, Single Nucleotide
- Reproducibility of Results
- DNA
- DNA, Single-Stranded
- Escherichia coli
- Graphite
- Nucleotides