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Regulation of immune responses in primary biliary cholangitis: a transcriptomic analysis of peripheral immune cells

1 Apr 2023

Abstract excerpt

BACKGROUND AIMS: In patients with primary biliary cholangitis (PBC), the serum liver biochemistry measured during treatment with ursodeoxycholic acid-the UDCA response-accurately predicts long-term outcome. Molecular characterization of patients stratified by UDCA response can improve biological understanding of the high-risk disease, thereby helping to identify alternative approaches to disease-modifying...

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PMID: 37026715
DOI: 10.1097/hc9.0000000000000110

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