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Identification of key genes and imbalance of immune cell infiltration in immunoglobulin A associated vasculitis nephritis by integrated bioinformatic analysis

21 Mar 2023

Abstract excerpt

Background: IgAV, the most common systemic vasculitis in childhood, is an immunoglobulin A-associated immune complex-mediated disease and its underlying molecular mechanisms are not fully understood. This study attempted to identify differentially expressed genes (DEGs) and find dysregulated immune cell types in IgAV to find the underlying pathogenesis for IgAVN. Methods: GSE102114 datasets were obtained from the...

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Share to Renal Diseases and Glomerulopathies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37026011
DOI: 10.3389/fimmu.2023.1087293

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